Overview
Celsius is the state-of-the-art controlled Freeze-Thaw system in pre-sterilized single use containers. Celsius provides the overall logistic solution offering a full line of disposable Celsius-Paks, Control Units, Freeze-Thaw Modules, Transfer Carts, Storage Modules and Shipping Units. Sartorius Stedim Biotech's patented technology enables flexible decoupling of operations during manufacturing of intermediates or purifed bulks. Batches of 4 L through 100 L are securely stored frozen for later processing.
Celsius Benefits
Improved Efficiency: Celsius dramatically improves the reproducibility and homogeneity of the product hence facilitating a successful validation. Celsius optimizes yields by avoiding product denaturation typical of uncontrolled methods. Celsius eliminates expensive and time-consuming cleaning. Overall processes benefit from a well-controlled and predictable operation.
Scalability: Celsius is optimally scalable. The Celsius S3 Freeze-Thaw Module, the bench-top system, is specifically designed for development and stability studies and allows Freeze-Thaw runs with as little as 30 mL of product under the same conditions as the production scale system.
Flexibility: The wide range of Celsius accessories provides the maximum logistic control. This allows solutions for short and long term storage, safe and protected handling of product, and shipping to other facilities.