UVivatec®
Virus inactivation based on UV-C irradiation

Virus inactivation with UVivatec is an integral part of the orthogonal virus clearance technology platform of Sartorius Stedim Biotech. This orthogonal platform features virus filtration, virus inactivation and virus adsorption. UVivatec shows efficient (> 4 log) inactivation of both small non-enveloped viruses (20 nm) e.g. PPV, MVM and larger enveloped viruses (> 50 nm) e.g. MuLV from biopharmaceutical feed streams by UV-C irradiation (254nm) while maintaining product integrity.

UVivatec is a state of the art virus inactivation technology with a novel helical reactor design providing uniform irradiation through efficient radial mixing based on dean vortices. UVivatec is a robust system with single-use modules for inactivation of viruses in:

  • Vaccines
  • Blood & plasma products
  • Proteins|enzymes out of tissue extracts
  • Fermentation media
  • Therapeutic proteins and|or Mabs